Daytime Presentations – 9:00am-5:00pm:

	Dr. Janis Taube Johns Hopkins Medical Institute Multiplex IF Biomarker Development Using the AstroPath Platform
	Kurt Schalper, MD, PhD Yale University School of Medicine Presentation
	Jared Burks, PhD MD Anderson Cancer Center Bringing Clarity to the Transcriptomic Targets through Spatial Proteomics
	Mike Angelo, MD PhD Stanford University Linking Tissue Structure to Single Cell Function using High Dimensional Tissue Imaging
	Michael Surace, PhD AstraZeneca GraphITE: An AI-Powered Scientist-Facing Exploration and Analysis Platform for Multiplex IF Image Data

Evening Break

Technology Presentations – 6:00pm-9:00pm:

• Lunaphore
• RareCyte
• Ultivue
• Akoya

Note: All presentations are being given in a live presentation format via Zoom and will also be recorded.  Attendees will be able to view the recordings for up to thirty-days after the event.

Presenter Bios

Michael R. Angelo, Stanford University

The Angelo lab uses custom built high dimensional imaging technologies and computational approaches to understand the interplay between single cell phenotype and tissue histology in health and disease.

They employ a method known as Multiplexed Ion Beam Imaging (MIBI) that uses secondary ion mass spectrometry to image antibodies tagged with isotopically pure elemental metal reporters. MIBI is capable of analyzing up to 100 targets simultaneously over a five-log dynamic range. Thus, MIBI enables highly multiplexed and sensitive immunohistochemistical analysis of complex tissues. The Angelo Lab applies MIBI to questions in the fields of cancer biology, infectious diseases, immune tolerance, allergy, and the maternal-fetal interface in addition to technology and methods development.

Jared Burks, PhD, MD Anderson Cancer Center

Dr. Jared Burks received his Ph.D. in Biology from Texas A&M University, focusing on viral protein trafficking in infected cells and conducted his postdoctoral work in Dr. Xing Li Wang’s group at Baylor continuing protein trafficking studies. Currently Dr. Burks is a Professor and Co-Director of the Flow Cytometry and Cellular Imaging Core Facility at MD Anderson Cancer Center. The core uses eight color imaging through the use of FFPE sampling and multispectral microscopy, live cell spinning disk confocal imaging, as well as established mass cytometry, CyTOF (imaging and suspension).

Kurt Schalper, MD, PhD, Yale University School of Medicine

Dr. Schalper trained as cell/molecular biologist and surgical pathologist. His professional experience includes molecular diagnostics and measurement of tissue biomarkers for companion diagnostics in cancer. Currently, he is an Assistant Professor of Pathology at Yale University and director of the Translational Immuno-oncology Laboratory at the Yale Cancer Center. His group aims to produce and support high quality translational research in immuno-oncology through standardized analyses of biomarkers and cross-integration with other Yale resources. These efforts could open new opportunities for biomarker discovery, identification of targets and patient selection for novel anti-cancer therapies.

Michael Surace, PhD, AstraZeneca

Michael Surace received a BS in Biology from JMU in 2004 before working as a laboratory technician in Pathology at UVA for two years. In 2006 he moved to Blacksburg, VA to pursue graduate studies in nuclear receptor/ TLR cell signaling crosstalk in the polarization of macrophage activation phenotypes. He received his PhD from Virginia Tech in 2010. He took two postdocs at MCV in Richmond, first in the Department of Anatomy and Neurobiology investigating the role of microglial activation in response to toxic insult in Parkinson’s Disease, then in Molecular Biology and Biochemistry, working on astrocytes as inflammatory immune cells in multiple sclerosis. In 2015 he joined STCube Pharmaceuticals as a research scientist where he started working with multiplex immunofluorescesce and image analysis to support mechanistic research, which led to his current position at Medimmune, as a scientist developing the company’s multiplex immunofluorescence program for research and clinical trials.

Dr. Janis Taube,  Johns Hopkins Medical Institute

Dr. Janis Taube is an associate professor of dermatology and pathology at the Johns Hopkins University School of Medicine and a member of the Johns Hopkins Kimmel Cancer Center. Her area of clinical expertise is dermatopathology. Dr. Taube serves as the Director of the Division of Dermatopathology and as the Assistant Director of the Dermatoimmunology Laboratory at the School of Medicine.
She is one of the lead scientific researchers in the Department of Dermatology at Johns Hopkins. Her research is related to the study of the B7-H1 molecule. Dr. Taube and her team are seeking to identify the signaling mechanisms behind B7-H1 expression.
She is a member of the College of American Pathologists, United States and Canadian Academy of Pathology, American Society of Dermatopathology and Dermatology Foundation.